About the Journal

Critical Comments in Biomedicine

Critical Comments in Biomedicine (CCB) is an electronic international review journal published semiannually by Shahid Sadoughi University of Medical Sciences. Review articles (including narrative reviews, systematic reviews, systematic review and meta-analyses, review of reviews), commentaries, hypotheses, letters to editors, and systematic review protocols written in the field of biomedicine are considered for publication in CCB. The journal particularly welcomes review articles with null findings and updated reviews. Although several reporting guidelines and checklists are developed to improve the reporting of systematic reviews and meta-analyses, and the majority of systematic reviews are now registered, they do not guarantee the quality of the published work, and their cautious evaluation is still needed. This is while the systematic reviews and meta-analyses published in the field of medicine are considered as the top-level evidence by researchers, professionals, and even politicians. Therefore the low-quality reviews might be misleading. Our team believes that professional journals like CCB might better evaluate such articles by gathering the experts interested in the field which makes the published evidence more reliable. The journal is dedicated to publishing review articles, only considering their quality without taking the manuscripts’ readership, their results, and the possibility of getting citations into account. CCB is an open-access journal and also does not charge a publication fee. 


Peer review process
Each received manuscript will be initially evaluated in terms of quality, innovation, the importance of the issue, and compliance with the journal's standards by the editors to save the authors and reviewers' time. In a maximum of 7 days, the authors will receive an e-mail containing the rejection or initial acceptance of their manuscript. Then, in the case that the manuscript meets the standards, it enters the double-blind peer-review process.
Each manuscript is sent to two specialized reviewers, if the reviewers differently respond to a manuscript, the manuscript will be sent to the third reviewer. Manuscripts may also be sent to a statistical specialist if needed.

Please note that:
- If the manuscript is not related to the journal's field of study, it will be rejected.
- The reviewers must have an advanced level of language proficiency and a high level of scientific competence in the subject area.
- The criteria for selecting the international reviewers include having appropriate experience in reviewing the related review articles.
- Authors can suggest the journal to send the manuscript to some specific reviewers or ask the journal to avoid selecting some reviewers (by mentioning their names) by mentioning the reason in the cover letter.
- All manuscripts are investigated through a double-blind peer-review process, while the authors and referees do not know each other.
- The final decision on all manuscripts is made by the editor-in-chief.
- The journal is committed to making quick decisions on manuscripts. We believe that an efficient writing process is a valuable service for authors and the scientific community, in general.
- If authors believe that the journal rejected their manuscript due to errors or misunderstandings of the scientific content, they can send an appeal to the journal's office using the journal's e-mail.


The manuscript may be returned to the corresponding author for modification of the scientific content and/or for language editions.
- The authors should highlight their edits within the text.
- The authors should send a letter in response to the reviewers' comments along with their edited manuscript.
- In the case that authors do not send their edited manuscript to the journal within two months, the revised manuscript will be considered as a new manuscript. So, the date of receipt will be corrected accordingly.
- If authors wish to re-submit a previously rejected article, they should also submit the original manuscript along with a letter about the details of changes.
- The editing process of the manuscript may be conducted in several steps.


The final version of the manuscript, before publication, will be sent to the corresponding author to check any possible typographical errors and other minor changes to avoid any mistakes. At this point, major changes are not accepted in the text. At this stage, authors should send the final proof to the editor-in-chief within two days.

The process to Manage Research and Publication Misconduct
The editorial board will incessantly work towards the observing publication misconduct such as redundant (duplicate) publication, plagiarism, fraudulent or fabricated data, changes in authorship, undisclosed conflict of interest, the ethical problem with a submitted manuscript, a reviewer who has appropriated an author’s idea or data, complaints against editors, etc. When the journal faces suspected cases of research and publication misconduct, the resolving process will be followed by guidelines provided by the "Committee on Publication Ethics (COPE)". The complete guidelines appear on the COPE website: https://publicationethics.org/.